ALDOA Polyclonal Antibody for Human(Homo sapiens) | EIAab.comALDOA Polyclonal Antibody for Human(Homo sapiens)

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ALDOA (Gene name),

Fructose-bisphosphate aldolase A (Protein name ), ALDOA_HUMAN from NCBI database.

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General Annotation

Antigen Annotation

Predicted Eptitope

Vaild Sequence

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Gene name:

ALDOA(ALDA);

Protein name:

Fructose-bisphosphate aldolase A;

Alternative:

Muscle-type aldolase;Lung cancer antigen NY-LU-1;

Organism:

Human (Homo sapiens).

General Annotation

Sub Unit:

Homotetramer. Interacts with SNX9 and WAS.

Function:

Plays a key role in glycolysis and gluconeogenesis. In addition, may also function as scaffolding protein.

Subcellular Location:

N/A

Protein Attributes:

Sequence length:

364

Sequence:

50:

100:

150:

200:

250:

300:

350:

364:

AAASESLFVS | NHAY

3D Structure:

N/A

Predicted Eptitope:

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Vaild Sequence:

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Related Databases

MIM:

103850

STRING:

9606.ENSP00000336927

SMR:

P04075

KEGG:

hsa:226

String:

P04075

Pfam:

PF00274

UniGene:

Hs.513490

Uniprot:

P04075

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ELISA Kit for Human Fructose-bisphosphate aldolase A

Cat.:

E1371r

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96T

ELISA Kit for Human Fructose-bisphosphate aldolase A

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ELISA Kit for Human Fructose-bisphosphate aldolase A

Cat.:

E1371m

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96T

ELISA Kit for Human Fructose-bisphosphate aldolase A

Cat.:

E1371h

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96T

CLIA Kit for Human Fructose-bisphosphate aldolase A

Cat.:

U1371m

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96T

CLIA Kit for Human Fructose-bisphosphate aldolase A

Cat.:

U1371r

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MSDS:

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Packing:

96T

CLIA Kit for Human Fructose-bisphosphate aldolase A

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U1371h

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96T

CLIA Kit for Human Fructose-bisphosphate aldolase A

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Polyclonal Antibody for Human Fructose-bisphosphate aldolase A

Cat.:

P1371Rb-h

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40ug/0.2ml

Polyclonal Antibody for Human Fructose-bisphosphate aldolase A

Cat.:

P1371Rb-r

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40ug/0.2ml

Polyclonal Antibody for Human Fructose-bisphosphate aldolase A

Cat.:

P1371Rb-m

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40ug/0.2ml

Monoclonal Antibody for Human Fructose-bisphosphate aldolase A

Protein for Human Fructose-bisphosphate aldolase A

R&D Technical Data

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Precision

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Recovery

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Linearity

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References

1.

"Nucleotide sequence of a cDNA clone for human aldolase: a messenger RNA in the liver."
Sakakibara M. , Mukai T. , Hori K.
Biochem. Biophys. Res. Commun.131:413-420(1985) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 1)
tissue: Liver.
2.

"A new human species of aldolase A mRNA from fibroblasts."
Izzo P. , Costanzo P. , Lupo A. , Rippa E. , Borghese A.M. , Paolella G. , Salvatore F.
Eur. J. Biochem.164:9-13(1987) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 1)
tissue: Fibroblast.
3.

"Human aldolase A gene. Structural organization and tissue-specific expression by multiple promoters and alternate mRNA processing."
Izzo P. , Costanzo P. , Lupo A. , Rippa E. , Paolella G. , Salvatore F.
Eur. J. Biochem.174:569-578(1988) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 1)
4.

"An additional promoter functions in the human aldolase A gene, but not in rat."
Mukai T. , Arai Y. , Yatsuki H. , Joh K. , Hori K.
Eur. J. Biochem.195:781-787(1991) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 1)
5.

"Complete sequencing and characterization of 21,243 full-length human cDNAs."
Ota T. , Suzuki Y. , Nishikawa T. , Otsuki T. , Sugiyama T. , Irie R. , Wakamatsu A. , Hayashi K. , Sato H. , Nagai K. , Kimura K. , Makita H. , Sekine M. , Obayashi M. , Nishi T. , Shibahara T. , Tanaka T. , Ishii S. , more...
Nat. Genet.36:40-45(2004) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 2)
tissue: Testis.
6.

"Cloning of human full open reading frames in Gateway(TM) system entry vector (pDONR201)."
Halleck A. , Ebert L. , Mkoundinya M. , Schick M. , Eisenstein S. , Neubert P. , Kstrang K. , Schatten R. , Shen B. , Henze S. , Mar W. , Korn B. , Zuo D. , Hu Y. , LaBaer J.
Submitted (2004-06) to the EMBL/GenBank/DDBJ databases

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 1)
7.

"The sequence and analysis of duplication-rich human chromosome 16."
Martin J. , Han C. , Gordon L.A. , Terry A. , Prabhakar S. , She X. , Xie G. , Hellsten U. , Chan Y.M. , Altherr M. , Couronne O. , Aerts A. , Bajorek E. , Black S. , Blumer H. , Branscomb E. , Brown N.C. , Bruno W.J. , more...
Nature432:988-994(2004) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]
8.

Mural R.J. , Istrail S. , Sutton G.G. , Florea L. , Halpern A.L. , Mobarry C.M. , Lippert R. , Walenz B. , Shatkay H. , Dew I. , Miller J.R. , Flanigan M.J. , Edwards N.J. , Bolanos R. , Fasulo D. , Halldorsson B.V. , Hannenhalli S. , Turner R. , more...
Submitted (2005-07) to the EMBL/GenBank/DDBJ databases

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]
9.

"The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
The MGC Project Team
Genome Res.14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 1)
tissue: Cervix.
tissue: Eye.
tissue: Lung.
tissue: Testis.
tissue: Uterus.
10.

"Characterization of three optional promoters in the 5' region of the human aldolase A gene."
Maire P. , Gautron S. , Hakim V. , Gregori C. , Mennecier F. , Kahn A.
J. Mol. Biol.197:425-438(1987) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA] OF 1-108 (ISOFORM 1)
11.

"The complete amino acid sequence of human skeletal-muscle fructose-bisphosphate aldolase."
Freemont P.S. , Dunbar B. , Fothergill-Gilmore L.A.
Biochem. J.249:779-788(1988) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: PROTEIN SEQUENCE OF 2-364
12.

"Human skeletal-muscle aldolase: N-terminal sequence analysis of CNBr- and o-iodosobenzoic acid-cleavage fragments."
Freemont P.S. , Dunbar B. , Fothergill L.A.
Arch. Biochem. Biophys.228:342-352(1984) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: PROTEIN SEQUENCE OF 2-63 AND 148-358
13.

"Exploring proteomes and analyzing protein processing by mass spectrometric identification of sorted N-terminal peptides."
Gevaert K. , Goethals M. , Martens L. , Van Damme J. , Staes A. , Thomas G.R. , Vandekerckhove J.
Nat. Biotechnol.21:566-569(2003) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: PROTEIN SEQUENCE OF 2-22
tissue: Platelet.
14.

"Identification of transglutaminase substrates in HT29 colon cancer cells: use of 5-(biotinamido)pentylamine as a transglutaminase-specific probe."
Lee K.N. , Maxwell M.D. , Patterson M.K. Jr. , Birckbichler P.J. , Conway E.
Biochim. Biophys. Acta1136:12-16(1992) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: PROTEIN SEQUENCE OF 2-16
tissue: Colon carcinoma.
15.

Lubec G. , Vishwanath V. , Chen W.-Q. , Sun Y.
Submitted (2008-12) to the UniProtKB

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: PROTEIN SEQUENCE OF 2-13; 29-42; 44-56; 61-69; 88-99; 154-173; 244-258 AND 332-342;IDENTIFICATION BY MASS SPECTROMETRY
tissue: Brain.
tissue: Cajal-Retzius cell.
tissue: Fetal brain cortex.
16.

"Evolutionary implications of the human aldolase-A, -B, -C, and -pseudogene chromosome locations."
Tolan D.R. , Niclas J. , Bruce B.D. , Lebo R.V.
Am. J. Hum. Genet.41:907-924(1987) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] OF 139-364 (ISOFORM 1/2)
17.

"Global, in vivo, and site-specific phosphorylation dynamics in signaling networks."
Olsen J.V. , Blagoev B. , Gnad F. , Macek B. , Kumar C. , Mortensen P. , Mann M.
Cell127:635-648(2006) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-46;IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]
tissue: Cervix carcinoma.
18.

"A quantitative atlas of mitotic phosphorylation."
Dephoure N. , Zhou C. , Villen J. , Beausoleil S.A. , Bakalarski C.E. , Elledge S.J. , Gygi S.P.
Proc. Natl. Acad. Sci. U.S.A.105:10762-10767(2008) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]
tissue: Cervix carcinoma.
19.

"Evolutionary conserved N-terminal region of human muscle fructose 1,6-bisphosphatase regulates its activity and the interaction with aldolase."
Gizak A. , Maciaszczyk E. , Dzugaj A. , Eschrich K. , Rakus D.
Proteins72:209-216(2008) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: INTERACTION WITH FBP2
20.

"Lys-N and trypsin cover complementary parts of the phosphoproteome in a refined SCX-based approach."
Gauci S. , Helbig A.O. , Slijper M. , Krijgsveld J. , Heck A.J. , Mohammed S.
Anal. Chem.81:4493-4501(2009) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]
21.

"Quantitative phosphoproteomic analysis of T cell receptor signaling reveals system-wide modulation of protein-protein interactions."
Mayya V. , Lundgren D.H. , Hwang S.-I. , Rezaul K. , Wu L. , Eng J.K. , Rodionov V. , Han D.K.
Sci. Signal.2:RA46-RA46(2009) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-36 AND SER-39;IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]
tissue: Leukemic T-cell.
22.

"Lysine acetylation targets protein complexes and co-regulates major cellular functions."
Choudhary C. , Kumar C. , Gnad F. , Nielsen M.L. , Rehman M. , Walther T.C. , Olsen J.V. , Mann M.
Science325:834-840(2009) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: ACETYLATION [LARGE SCALE ANALYSIS] AT LYS-42; LYS-108 AND LYS-330;IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]
23.

"Quantitative phosphoproteomics reveals widespread full phosphorylation site occupancy during mitosis."
Olsen J.V. , Vermeulen M. , Santamaria A. , Kumar C. , Miller M.L. , Jensen L.J. , Gnad F. , Cox J. , Jensen T.S. , Nigg E.A. , Brunak S. , Mann M.
Sci. Signal.3:RA3-RA3(2010) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-36 AND SER-39;IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]
tissue: Cervix carcinoma.
24.

"Initial characterization of the human central proteome."
Burkard T.R. , Planyavsky M. , Kaupe I. , Breitwieser F.P. , Buerckstuemmer T. , Bennett K.L. , Superti-Furga G. , Colinge J.
BMC Syst. Biol.5:17-17(2011) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]
25.

"The first identification of lysine malonylation substrates and its regulatory enzyme."
Peng C. , Lu Z. , Xie Z. , Cheng Z. , Chen Y. , Tan M. , Luo H. , Zhang Y. , He W. , Yang K. , Zwaans B.M. , Tishkoff D. , Ho L. , Lombard D. , He T.C. , Dai J. , Verdin E. , Ye Y. , more...
Mol. Cell. Proteomics10:M111.012658.01-M111.012658.12(2011) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: MALONYLATION AT LYS-111 AND LYS-312
26.

"System-wide temporal characterization of the proteome and phosphoproteome of human embryonic stem cell differentiation."
Rigbolt K.T. , Prokhorova T.A. , Akimov V. , Henningsen J. , Johansen P.T. , Kratchmarova I. , Kassem M. , Mann M. , Olsen J.V. , Blagoev B.
Sci. Signal.4:RS3-RS3(2011) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-39 AND SER-46;IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]
27.

"N-terminal acetylome analyses and functional insights of the N-terminal acetyltransferase NatB."
Van Damme P. , Lasa M. , Polevoda B. , Gazquez C. , Elosegui-Artola A. , Kim D.S. , De Juan-Pardo E. , Demeyer K. , Hole K. , Larrea E. , Timmerman E. , Prieto J. , Arnesen T. , Sherman F. , Gevaert K. , Aldabe R.
Proc. Natl. Acad. Sci. U.S.A.109:12449-12454(2012) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]
28.

"The crystal structure of human muscle aldolase at 3.0-A resolution."
Gamblin S.J. , Cooper B. , Millar J.R. , Davies G.J. , Littlechild J.A. , Watson H.C.
FEBS Lett.262:282-286(1990) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: X-RAY CRYSTALLOGRAPHY (3.0 ANGSTROMS)
29.

"Activity and specificity of human aldolases."
Gamblin S.J. , Davies G.J. , Grimes J.M. , Jackson R.M. , Littlechild J.A. , Watson H.C.
J. Mol. Biol.219:573-576(1991) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: X-RAY CRYSTALLOGRAPHY (2.0 ANGSTROMS)
30.

"Crystal structure of human muscle aldolase complexed with fructose 1,6-bisphosphate: mechanistic implications."
Dalby A. , Dauter Z. , Littlechild J.A.
Protein Sci.8:291-297(1999) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: X-RAY CRYSTALLOGRAPHY (2.8 ANGSTROMS)
31.

"Human aldolase A deficiency associated with a hemolytic anemia: thermolabile aldolase due to a single base mutation."
Kishi H. , Mukai T. , Hirono A. , Fujii H. , Miwa S. , Hori K.
Proc. Natl. Acad. Sci. U.S.A.84:8623-8627(1987) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: VARIANT GSD12 GLY-129;CHARACTERIZATION OF VARIANT GSD12 GLY-129
32.

"Human aldolase A of a hemolytic anemia patient with Asp-128-->Gly substitution: characteristics of an enzyme generated in E. coli transfected with the expression plasmid pHAAD128G."
Takasaki Y. , Takahashi I. , Mukai T. , Hori K.
J. Biochem.108:153-157(1990) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: CHARACTERIZATION OF VARIANT GSD12 GLY-129
33.

"Human aldolase A natural mutants: relationship between flexibility of the C-terminal region and enzyme function."
Esposito G. , Vitagliano L. , Costanzo P. , Borrelli L. , Barone R. , Pavone L. , Izzo P. , Zagari A. , Salvatore F.
Biochem. J.380:51-56(2004) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: VARIANT GSD12 SER-347;BIOPHYSICOCHEMICAL PROPERTIES;CHARACTERIZATION OF VARIANTS GSD12 LYS-207 AND SER-347
34.

"Brief report: inherited metabolic myopathy and hemolysis due to a mutation in aldolase A."
Kreuder J. , Borkhardt A. , Repp R. , Pekrun A. , Goettsche B. , Gottschalk U. , Reichmann H. , Schachenmayr W. , Schlegel K. , Lampert F.
N. Engl. J. Med.334:1100-1104(1996) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: VARIANT GSD12 LYS-207
35.

"Hemolytic anemia and severe rhabdomyolysis caused by compound heterozygous mutations of the gene for erythrocyte/muscle isozyme of aldolase, ALDOA(Arg303X/Cys338Tyr)."
Yao D.C. , Tolan D.R. , Murray M.F. , Harris D.J. , Darras B.T. , Geva A. , Neufeld E.J.
Blood103:2401-2403(2004) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: VARIANT GSD12 TYR-339

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